Meziane H - Schaller F - Bauer S - Villard C - Matarazzo V - Riet F - Guillon G - Lafitte D - Desarmenien MG - Tauber M - Muscatelli F


Biological psychiatry


Mutations of MAGEL2 have been reported in patients presenting with autism, and loss of MAGEL2 is also associated with Prader-Willi syndrome, a neurodevelopmental genetic disorder. This study aimed to determine the behavioral phenotype of Magel2-deficient adult mice, to characterize the central oxytocin (OT) system of these mutant mice, and to test the curative effect of a peripheral OT treatment just after birth.

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