Auteurs
Renolleau S - Aggoun-Zouaoui D - Ben-Ari Y - Charriaut-Marlangue C
Journal
Stroke
Abstract
The mechanisms leading to delayed cell death after hypoxic-ischemic injury in the developing brain remain to be elucidated. The aim of this study was to develop a model of transient focal ischemia in the neonatal rat in an attempt to create a reperfusion phase since in the filament model of reversible middle cerebral artery occlusion, size limitations precluded performing this procedure before 14 to 18 days. We then analyze whether apoptosis or necrosis occurs in this model.
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