Emergence of organization and computation in neural circuits
Julijana Gjorgjieva
Technical University of Munich – School of Life Sciences

Résumé
Synapses and neuronal properties in neural circuits are constantly modified by various plasticity mechanisms operating at different timescales during development and learning. While extensive experimental studies have characterized these plasticity mechanisms, understanding their functional implications is challenging due to their interplay, and the complexity induced by the diversity of cell types. Combining theoretical analysis and computational modeling, I will discuss how different plasticity mechanisms refine connectivity giving rise to structures such as E-I co-tuning and lateral inhibition, especially in early stages of development when the circuits generate their own, spontaneous activity. I will show what these different connectivity structures imply in terms of computations, and how they can be further modified by contextual signals.

Invitée par Lorenzo Fontolan
Lundi 19 janvier 2026, à 11h – salle de conférence de l’Inmed