Auteurs
Silva-Hurtado TJ - Giua G - Lassalle O - Makrini-Maleville L - Strauss B - Wager-Miller J - Freyermuth JM - Mackie K - Valjent E - Manzoni OJJ - Chavis P
Journal
Biological psychiatry global open science
Abstract
Adolescent cannabinoid exposure can have long-lasting effects on the brain, particularly in the prefrontal cortex, where the reelin protein plays a crucial role in neural organization. Chronic cannabinoid exposure leads to reelin deficiency and behavioral abnormalities, but the underlying mechanisms remain unclear. With the increasing use of synthetic cannabinoids (SCs) among young people, understanding these effects is crucial.