Auteurs
Morales-Navas M - Castaño-Castaño S - Pérez-Fernández C - Sánchez-Gil A - Teresa Colomina M - Leinekugel X - Sánchez-Santed F
Journal
International journal of environmental research and public health
Abstract
In recent years, ultrasonic vocalizations (USV) in pups has become established as a good tool for evaluating behaviors related to communication deficits and emotional states observed in autism spectrum disorder (ASD). Prenatal valproic acid (VPA) exposure leads to impairments and social behavior deficits associated with autism, with the effects of VPA being considered as a reliable animal model of ASD. Some studies also suggest that prenatal exposure to chlorpyrifos (CPF) could enhance autistic-like behaviors.